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Continuous Positive Airway Pressure versus Oral Appliance Treatment for Obstructive Sleep Apnea

A Randomized Controlled Trial
Posted on 10/9/2018 by Nelson R. Diers

At A Glance Commentary

Scientific Knowledge on the Subject

Continuous positive airway pressure (CPAP) is considered to be the treatment of choice for obstructive sleep apnea (OSA). Oral appliance (OA) therapy, such as the mandibular advancement device (MAD), is a viable alternative with growing use, particularly in patients with milder OSA. Comparative effectiveness studies that examine multiple important health outcomes with these treatment modalities in patients with the full spectrum of OSA severity are lacking.

What This Study Adds to the Field

In the short term, health outcomes in patients with moderate to severe OSA were similar after treatment with CPAP and MAD. This was likely explained by the greater efficacy of CPAP being offset by inferior compliance relative to MAD. These findings strongly challenge current practice parameters recommending MAD treatment be considered only in patients with mild to moderate OSA. Long-term comparative effectiveness studies between CPAP and MAD that include objectively measured treatment compliance are needed to better define treatment strategies for patients with OSA."

- Study & information source: Health Outcomes of Continuous Positive Airway Pressure versus Oral Appliance Treatment
for Obstructive Sleep Apnea
. View the provided document to view more in-depth information.

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